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Computer aided screening of potent inhibitor compounds against inhibitor resistant TEM β-lactamase mutants from traditional Chinese medicine

Inhibitor-resistant TEM (IRT) type β-lactamase mutation is largely known. Therefore, it is of interest to identify new yet improved leads against IRT from traditional Chinese medicine. Hence, we screened more than 10,000 compounds from Chinese medicine (tcm@taiwan database) with mutant molecular IRT...

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Podrobná bibliografie
Vydáno v:Bioinformation
Hlavní autoři: Zhu, Qifeng, Yin, Yanxia, Liu, Hanjie, Tian, Jinhong
Médium: Artigo
Jazyk:Inglês
Vydáno: Biomedical Informatics 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4312368/
https://ncbi.nlm.nih.gov/pubmed/25670878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6026/97320630010750
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