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Computer aided screening of potent inhibitor compounds against inhibitor resistant TEM β-lactamase mutants from traditional Chinese medicine

Inhibitor-resistant TEM (IRT) type β-lactamase mutation is largely known. Therefore, it is of interest to identify new yet improved leads against IRT from traditional Chinese medicine. Hence, we screened more than 10,000 compounds from Chinese medicine (tcm@taiwan database) with mutant molecular IRT...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Bioinformation
Hauptverfasser: Zhu, Qifeng, Yin, Yanxia, Liu, Hanjie, Tian, Jinhong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Biomedical Informatics 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4312368/
https://ncbi.nlm.nih.gov/pubmed/25670878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6026/97320630010750
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