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Characterization of Acute Biliary Hyperplasia in Fisher 344 Rats Administered the Indole-3-Carbinol Analog, NSC-743380
NSC-743380 (1-[(3-chlorophenyl)-methyl]-1H-indole-3-carbinol) is in early stages of development as an anticancer agent. Two metabolites reflect sequential conversion of the carbinol functionality to a carboxaldehyde and the major metabolite, 1-[(3-chlorophenyl)-methyl]-1H-indole-3- carboxylic acid....
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| Publicado no: | Toxicol Appl Pharmacol |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4312220/ https://ncbi.nlm.nih.gov/pubmed/25448049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2014.10.015 |
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