Characterization of Acute Biliary Hyperplasia in Fisher 344 Rats Administered the Indole-3-Carbinol Analog, NSC-743380

NSC-743380 (1-[(3-chlorophenyl)-methyl]-1H-indole-3-carbinol) is in early stages of development as an anticancer agent. Two metabolites reflect sequential conversion of the carbinol functionality to a carboxaldehyde and the major metabolite, 1-[(3-chlorophenyl)-methyl]-1H-indole-3- carboxylic acid....

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Detaylı Bibliyografya
Yayımlandı:Toxicol Appl Pharmacol
Asıl Yazarlar: Eldridge, Sandy R., Covey, Joseph, Morris, Joel, Fang, Bingliang, Horn, Thomas L., Elsass, Karen E., Hamre, John R., McCormick, David L., Davis, Myrtle A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4312220/
https://ncbi.nlm.nih.gov/pubmed/25448049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2014.10.015
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