Impact of Methionine Oxidation on Calmodulin Structural Dynamics

We have used electron paramagnetic resonance (EPR) to examine the structural impact of oxidizing specific methionine (M) side chains in calmodulin (CaM). It has been shown that oxidation of either M109 or M124 in CaM diminishes CaM regulation of the muscle calcium release channel, the ryanodine rece...

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Bibliografske podrobnosti
izdano v:Biochem Biophys Res Commun
Main Authors: McCarthy, Megan R., Thompson, Andrew R., Nitu, Florentin, Moen, Rebecca J., Olenek, Michael J., Klein, Jennifer C., Thomas, David D.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4312012/
https://ncbi.nlm.nih.gov/pubmed/25478640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2014.11.091
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