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Isoprenoid Precursor Biosynthesis Is the Essential Metabolic Role of the Apicoplast during Gametocytogenesis in Plasmodium falciparum

The malaria parasite harbors a relict plastid called the apicoplast and its discovery opened a new avenue for drug discovery and development due to its unusual, nonmammalian metabolism. The apicoplast is essential during the asexual intraerythrocytic and hepatic stages of the parasite, and there is...

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Détails bibliographiques
Publié dans:Eukaryot Cell
Auteurs principaux: Wiley, Jessica D., Merino, Emilio F., Krai, Priscilla M., McLean, Kyle J., Tripathi, Abhai K., Vega-Rodríguez, Joel, Jacobs-Lorena, Marcelo, Klemba, Michael, Cassera, Maria B.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4311923/
https://ncbi.nlm.nih.gov/pubmed/25446055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00198-14
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