Therapy with Plasma Purified Alpha1-Antitrypsin (Prolastin(®)) Induces Time-Dependent Changes in Plasma Levels of MMP-9 and MPO

The common Z mutation (Glu342Lys) of α1-antitrypsin (A1AT) results in the polymerization and intracellular retention of A1AT protein. The concomitant deficiency of functional A1AT predisposes PiZZ subjects to early onset emphysema. Clinical studies have implied that, among the biomarkers associated...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:PLoS One
मुख्य लेखकों: Koepke, Janine, Dresel, Marc, Schmid, Severin, Greulich, Timm, Beutel, Björn, Schmeck, Bernd, Vogelmeier, Claus Franz, Janciauskiene, Sabina, Koczulla, Andreas Rembert
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2015
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4311911/
https://ncbi.nlm.nih.gov/pubmed/25635861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117497
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