The effects of weekly augmentation therapy in patients with PiZZ α1-antitrypsin deficiency

BACKGROUND: The major concept behind augmentation therapy with human α(1)-antitrypsin (AAT) is to raise the levels of AAT in patients with protease inhibitor phenotype ZZ (Glu342Lys)-inherited AAT deficiency and to protect lung tissues from proteolysis and progression of emphysema. OBJECTIVE: To eva...

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Main Authors: Schmid, ST, Koepke, J, Dresel, M, Hattesohl, A, Frenzel, E, Perez, J, Lomas, DA, Miranda, E, Greulich, T, Noeske, S, Wencker, M, Teschler, H, Vogelmeier, C, Janciauskiene, S, Koczulla, AR
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2012
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468059/
https://ncbi.nlm.nih.gov/pubmed/23055718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/COPD.S34560
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