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Dried whole-plant Artemisia annua slows evolution of malaria drug resistance and overcomes resistance to artemisinin

Pharmaceutical monotherapies against human malaria have proven effective, although ephemeral, owing to the inevitable evolution of resistant parasites. Resistance to two or more drugs delivered in combination will evolve more slowly; hence combination therapies have become the preferred norm in the...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Elfawal, Mostafa A., Towler, Melissa J., Reich, Nicholas G., Weathers, Pamela J., Rich, Stephen M.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4311864/
https://ncbi.nlm.nih.gov/pubmed/25561559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1413127112
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