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Dried whole-plant Artemisia annua slows evolution of malaria drug resistance and overcomes resistance to artemisinin

Pharmaceutical monotherapies against human malaria have proven effective, although ephemeral, owing to the inevitable evolution of resistant parasites. Resistance to two or more drugs delivered in combination will evolve more slowly; hence combination therapies have become the preferred norm in the...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Elfawal, Mostafa A., Towler, Melissa J., Reich, Nicholas G., Weathers, Pamela J., Rich, Stephen M.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4311864/
https://ncbi.nlm.nih.gov/pubmed/25561559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1413127112
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