Acceleration of conduction velocity linked to clustering of nodal components precedes myelination

High-density accumulation of voltage-gated sodium (Na(v)) channels at nodes of Ranvier ensures rapid saltatory conduction along myelinated axons. To gain insight into mechanisms of node assembly in the CNS, we focused on early steps of nodal protein clustering. We show in hippocampal cultures that p...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Freeman, Sean A., Desmazières, Anne, Simonnet, Jean, Gatta, Marie, Pfeiffer, Friederike, Aigrot, Marie Stéphane, Rappeneau, Quentin, Guerreiro, Serge, Michel, Patrick Pierre, Yanagawa, Yuchio, Barbin, Gilles, Brophy, Peter J., Fricker, Desdemona, Lubetzki, Catherine, Sol-Foulon, Nathalie
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4311839/
https://ncbi.nlm.nih.gov/pubmed/25561543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1419099112
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados