A KIR B centromeric region present in Africans but not Europeans protects pregnant women from pre-eclampsia

In sub-Saharan Africans, maternal mortality is unacceptably high, with >400 deaths per 100,000 births compared with <10 deaths per 100,000 births in Europeans. One-third of the deaths are caused by pre-eclampsia, a syndrome arising from defective placentation. Controlling placentation are mate...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Nakimuli, Annettee, Chazara, Olympe, Hiby, Susan E., Farrell, Lydia, Tukwasibwe, Stephen, Jayaraman, Jyothi, Traherne, James A., Trowsdale, John, Colucci, Francesco, Lougee, Emma, Vaughan, Robert W., Elliott, Alison M., Byamugisha, Josaphat, Kaleebu, Pontiano, Mirembe, Florence, Nemat-Gorgani, Neda, Parham, Peter, Norman, Paul J., Moffett, Ashley
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2015
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Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4311823/
https://ncbi.nlm.nih.gov/pubmed/25561558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1413453112
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