Formation of nanoparticles by cooperative inclusion between (S)-camptothecin-modified dextrans and β-cyclodextrin polymers

Novel (S)-camptothecin–dextran polymers were obtained by “click” grafting of azide-modified (S)-camptothecin and alkyne-modified dextrans. Two series based on 10 kDa and 70 kDa dextrans were prepared with a degree of substitution of (S)-camptothecin between 3.1 and 10.2%. The binding properties with...

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Pubblicato in:Beilstein J Org Chem
Autori principali: Nielsen, Thorbjørn Terndrup, Amiel, Catherine, Duroux, Laurent, Larsen, Kim Lambertsen, Städe, Lars Wagner, Wimmer, Reinhard, Wintgens, Véronique
Natura: Artigo
Lingua:Inglês
Pubblicazione: Beilstein-Institut 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4311650/
https://ncbi.nlm.nih.gov/pubmed/25670998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.11.14
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