Relationship between promoter methylation & tissue expression of MGMT gene in ovarian cancer

BACKGROUND & OBJECTIVES: Epigenetic alterations, in addition to multiple gene abnormalities, are involved in the genesis and progression of human cancers. Aberrant methylation of CpG islands within promoter regions is associated with transcriptional inactivation of various tumour suppressor gene...

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Vydáno v:Indian J Med Res
Hlavní autoři: Shilpa, V., Bhagat, Rahul, Premalata, C.S., Pallavi, V.R., Ramesh, G., Krishnamoorthy, Lakshmi
Médium: Artigo
Jazyk:Inglês
Vydáno: Medknow Publications & Media Pvt Ltd 2014
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4311314/
https://ncbi.nlm.nih.gov/pubmed/25579142
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