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Comparative risk assessment of alcohol, tobacco, cannabis and other illicit drugs using the margin of exposure approach

A comparative risk assessment of drugs including alcohol and tobacco using the margin of exposure (MOE) approach was conducted. The MOE is defined as ratio between toxicological threshold (benchmark dose) and estimated human intake. Median lethal dose values from animal experiments were used to deri...

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Publicat a:Sci Rep
Autors principals: Lachenmeier, Dirk W., Rehm, Jürgen
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4311234/
https://ncbi.nlm.nih.gov/pubmed/25634572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08126
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