Subcellular localization of phospholipase Cζ in human sperm and its absence in DPY19L2-deficient sperm are consistent with its role in oocyte activation

We recently identified the DPY19L2 gene as the main genetic cause of human globozoospermia (70%) and described that Dpy19l2 knockout (KO) mice faithfully reproduce the human phenotype of globozoospermia making it an excellent model to characterize the molecular physiopathology of globozoospermia. Re...

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Foilsithe in:Mol Hum Reprod
Main Authors: Escoffier, Jessica, Yassine, Sandra, Lee, Hoi Chang, Martinez, Guillaume, Delaroche, Julie, Coutton, Charles, Karaouzène, Thomas, Zouari, Raoudha, Metzler-Guillemain, Catherine, Pernet-Gallay, Karin, Hennebicq, Sylviane, Ray, Pierre F., Fissore, Rafael, Arnoult, Christophe
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2015
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Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4311148/
https://ncbi.nlm.nih.gov/pubmed/25354701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molehr/gau098
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