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SIK2 regulates CRTCs, HDAC4 and glucose uptake in adipocytes

Salt-inducible kinase 2 (SIK2) is an AMP-activated protein kinase (AMPK) related kinase abundantly expressed in adipose tissue. Our aim was to identify molecular targets and functions of SIK2 in adipocytes, and to address the role of PKA-mediated phosphorylation of SIK2 on Ser358. Modulation of SIK2...

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Bibliografiske detaljer
Udgivet i:J Cell Sci
Main Authors: Henriksson, Emma, Säll, Johanna, Gormand, Amélie, Wasserstrom, Sebastian, Morrice, Nicholas A., Fritzen, Andreas M., Foretz, Marc, Campbell, David G., Sakamoto, Kei, Ekelund, Mikael, Degerman, Eva, Stenkula, Karin G., Göransson, Olga
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4311129/
https://ncbi.nlm.nih.gov/pubmed/25472719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.153932
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