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SIK2 regulates CRTCs, HDAC4 and glucose uptake in adipocytes

Salt-inducible kinase 2 (SIK2) is an AMP-activated protein kinase (AMPK) related kinase abundantly expressed in adipose tissue. Our aim was to identify molecular targets and functions of SIK2 in adipocytes, and to address the role of PKA-mediated phosphorylation of SIK2 on Ser358. Modulation of SIK2...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Henriksson, Emma, Säll, Johanna, Gormand, Amélie, Wasserstrom, Sebastian, Morrice, Nicholas A., Fritzen, Andreas M., Foretz, Marc, Campbell, David G., Sakamoto, Kei, Ekelund, Mikael, Degerman, Eva, Stenkula, Karin G., Göransson, Olga
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4311129/
https://ncbi.nlm.nih.gov/pubmed/25472719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.153932
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