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Glycogen-synthase kinase-3β is decreased in peripheral blood mononuclear cells of patients with mild cognitive impairment
Glycogen-synthase kinase-3 (GSK-3) plays a central role in Alzheimer’s disease (AD). It is involved in the hyper-phosphorylation of Tau and the increased production of β-amyloid. Despite its eminent role, only one study has been published so far in AD blood samples, reporting an increase of GSK-3α a...
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| Опубликовано в: : | Exp Gerontol |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4311052/ https://ncbi.nlm.nih.gov/pubmed/19249342 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2009.02.007 |
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