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Postulated deficiency of hepatic heme and repair by hematin infusions in the "inducible" hepatic porphyrias.

There is compelling, indirect evidence of hepatic heme deficiency due primarily to the respective genetic errors of the three inducible hepatic porphyrias, acute intermittent porphyria, porphyria variegata, and hereditary coproporphyria. The induction is enhanced by exogenous inducers such as barbit...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Watson, C J, Pierach, C A, Bossenmaier, I, Cardinal, R
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1977
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC431086/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/266732/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.5.2118
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