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Repression by Hematin of Porphyrin Biosynthesis in Erythrocyte Precursors in Congenital Erythropoietic Porphyria

Hematin administered intravenously in a patient with congenital erythropoietic porphyria evidently entered erythrocyte precursors in the bone marrow, producing the well-known negative feedback repression of porphyrin biosynthesis with marked decline of porphyrin concentrations in urine, circulating...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Watson, C. J., Bossenmaier, I., Cardinal, R., Petryka, Z. J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1974
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC387986/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4521800/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.2.278
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