Detection of C3d-Binding Donor-Specific Anti-HLA Antibodies at Diagnosis of Humoral Rejection Predicts Renal Graft Loss

Antibody-mediated rejection (AMR) is a major cause of kidney graft loss, yet assessment of individual risk at diagnosis is impeded by the lack of a reliable prognosis assay. Here, we tested whether the capacity of anti-HLA antibodies to bind complement components allows accurate risk stratification...

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Udgivet i:J Am Soc Nephrol
Main Authors: Sicard, Antoine, Ducreux, Stéphanie, Rabeyrin, Maud, Couzi, Lionel, McGregor, Brigitte, Badet, Lionel, Scoazec, Jean Yves, Bachelet, Thomas, Lepreux, Sébastien, Visentin, Jonathan, Merville, Pierre, Fremeaux-Bacchi, Véronique, Morelon, Emmanuel, Taupin, Jean-Luc, Dubois, Valérie, Thaunat, Olivier
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Nephrology 2015
Fag:
Clinical Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4310653/
https://ncbi.nlm.nih.gov/pubmed/25125383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013101144
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