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Activation of Hypoxia-Inducible Factors Prevents Diabetic Nephropathy

Hyperglycemia results in increased oxygen consumption and decreased oxygen tension in the kidney. We tested the hypothesis that activation of hypoxia-inducible factors (HIFs) protects against diabetes-induced alterations in oxygen metabolism and kidney function. Experimental groups consisted of cont...

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Détails bibliographiques
Publié dans:J Am Soc Nephrol
Auteurs principaux: Nordquist, Lina, Friederich-Persson, Malou, Fasching, Angelica, Liss, Per, Shoji, Kumi, Nangaku, Masaomi, Hansell, Peter, Palm, Fredrik
Format: Artigo
Langue:Inglês
Publié: American Society of Nephrology 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4310648/
https://ncbi.nlm.nih.gov/pubmed/25183809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013090990
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