Transient Inability to manage Proteobacteria promotes chronic gut inflammation in TLR5-deficient mice

Colitis results from breakdown of homeostasis between intestinal microbiota and the mucosal immune system, with both environmental and genetic influencing factors. Flagellin receptor TLR5-deficient mice (T5KO) display elevated intestinal pro-inflammatory gene expression and colitis with incomplete p...

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Bibliografiset tiedot
Julkaisussa:Cell Host Microbe
Päätekijät: Carvalho, Frederic A., Koren, Omry, Goodrich, Julia K., Johansson, Malin E. V., Nalbantoglu, Ilke, Aitken, Jesse D., Su, Yueju, Chassaing, Benoit, Walters, William A., González, Antonio, Clemente, Jose C., Cullender, Tyler C., Barnich, Nicolas, Darfeuille-Michaud, Arlette, Vijay-Kumar, Matam, Knight, Rob, Ley, Ruth E., Gewirtz, Andrew T.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4310462/
https://ncbi.nlm.nih.gov/pubmed/22863420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2012.07.004
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