Early Activation of the Kynurenine Pathway Predicts Early Death and Long‐term Outcome in Patients Resuscitated From Out‐of‐Hospital Cardiac Arrest

BACKGROUND: The kynurenine pathway (KP) is the major route of tryptophan (TRP) catabolism and is activated by inflammation and after cardiac arrest in animals. We hypothesized that the KP activation level correlates with severity of post–cardiac arrest shock, early death, and long‐term outcome. METH...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Am Heart Assoc
Auteurs principaux: Ristagno, Giuseppe, Latini, Roberto, Vaahersalo, Jukka, Masson, Serge, Kurola, Jouni, Varpula, Tero, Lucchetti, Jacopo, Fracasso, Claudia, Guiso, Giovanna, Montanelli, Alessandro, Barlera, Simona, Gobbi, Marco, Tiainen, Marjaana, Pettilä, Ville, Skrifvars, Markus B.
Format: Artigo
Langue:Inglês
Publié: Blackwell Publishing Ltd 2014
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4310405/
https://ncbi.nlm.nih.gov/pubmed/25092787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.114.001094
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