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Early Activation of the Kynurenine Pathway Predicts Early Death and Long‐term Outcome in Patients Resuscitated From Out‐of‐Hospital Cardiac Arrest

BACKGROUND: The kynurenine pathway (KP) is the major route of tryptophan (TRP) catabolism and is activated by inflammation and after cardiac arrest in animals. We hypothesized that the KP activation level correlates with severity of post–cardiac arrest shock, early death, and long‐term outcome. METH...

詳細記述

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書誌詳細
出版年:J Am Heart Assoc
主要な著者: Ristagno, Giuseppe, Latini, Roberto, Vaahersalo, Jukka, Masson, Serge, Kurola, Jouni, Varpula, Tero, Lucchetti, Jacopo, Fracasso, Claudia, Guiso, Giovanna, Montanelli, Alessandro, Barlera, Simona, Gobbi, Marco, Tiainen, Marjaana, Pettilä, Ville, Skrifvars, Markus B.
フォーマット: Artigo
言語:Inglês
出版事項: Blackwell Publishing Ltd 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4310405/
https://ncbi.nlm.nih.gov/pubmed/25092787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.114.001094
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