Early Activation of the Kynurenine Pathway Predicts Early Death and Long‐term Outcome in Patients Resuscitated From Out‐of‐Hospital Cardiac Arrest

BACKGROUND: The kynurenine pathway (KP) is the major route of tryptophan (TRP) catabolism and is activated by inflammation and after cardiac arrest in animals. We hypothesized that the KP activation level correlates with severity of post–cardiac arrest shock, early death, and long‐term outcome. METH...

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Bibliografiska uppgifter
I publikationen:J Am Heart Assoc
Huvudupphovsmän: Ristagno, Giuseppe, Latini, Roberto, Vaahersalo, Jukka, Masson, Serge, Kurola, Jouni, Varpula, Tero, Lucchetti, Jacopo, Fracasso, Claudia, Guiso, Giovanna, Montanelli, Alessandro, Barlera, Simona, Gobbi, Marco, Tiainen, Marjaana, Pettilä, Ville, Skrifvars, Markus B.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Blackwell Publishing Ltd 2014
Ämnen:
Original Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4310405/
https://ncbi.nlm.nih.gov/pubmed/25092787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.114.001094
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