Loading...

Diffuse binding of Zn(2+) to the denatured ensemble of Cu/Zn superoxide dismutase 1

The stability and structural properties of the metalloprotein superoxide dismutase 1 (SOD1) are found to depend critically on metal ions. Native SOD1 monomers coordinate one structural Zn(2+) and one redox-active Cu(2+/1+) to the active site. To do this, the Zn(2+) ions need to interact with the SOD...

Full description

Saved in:
Bibliographic Details
Published in:FEBS Open Bio
Main Authors: Szpryngiel, Scarlett, Oliveberg, Mikael, Mäler, Lena
Format: Artigo
Language:Inglês
Published: Elsevier 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4309841/
https://ncbi.nlm.nih.gov/pubmed/25685664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fob.2014.12.003
Tags: Add Tag
No Tags, Be the first to tag this record!