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Augmented cystine-glutamate exchange by pituitary adenylate cyclase-activating polypeptide signaling via the VPAC1 receptor
In the central nervous system, cystine import in exchange for glutamate through system x(c)(−) is critical for the production of the antioxidant glutathione by astrocytes, as well as the maintenance of extracellular glutamate. Therefore, regulation of system x(c)(−) activity affects multiple aspects...
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| Udgivet i: | Synapse |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4309754/ https://ncbi.nlm.nih.gov/pubmed/25066643 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/syn.21772 |
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