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Augmented cystine-glutamate exchange by pituitary adenylate cyclase-activating polypeptide signaling via the VPAC1 receptor

In the central nervous system, cystine import in exchange for glutamate through system x(c)(−) is critical for the production of the antioxidant glutathione by astrocytes, as well as the maintenance of extracellular glutamate. Therefore, regulation of system x(c)(−) activity affects multiple aspects...

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Podrobná bibliografie
Vydáno v:Synapse
Hlavní autoři: Resch, Jon M., Albano, Rebecca, Liu, XiaoQian, Hjelmhaug, Julie, Lobner, Doug, Baker, David A., Choi, SuJean
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4309754/
https://ncbi.nlm.nih.gov/pubmed/25066643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/syn.21772
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