A Neuron-Specific Deletion of the MicroRNA-Processing Enzyme DICER Induces Severe but Transient Obesity in Mice

MicroRNAs (miRNAs) are small, non-coding RNA molecules that regulate gene expression post-transcriptionally. MiRNAs are implicated in various biological processes associated with obesity, including adipocyte differentiation and lipid metabolism. We used a neuronal-specific inhibition of miRNA matura...

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Veröffentlicht in:PLoS One
Hauptverfasser: Mang, Géraldine M., Pradervand, Sylvain, Du, Ngoc-Hien, Arpat, Alaaddin Bulak, Preitner, Frédéric, Wigger, Leonore, Gatfield, David, Franken, Paul
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4309537/
https://ncbi.nlm.nih.gov/pubmed/25629159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116760
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