Structural Insights into the Tumor-Promoting Function of the MTDH-SND1 Complex

Metadherin (MTDH) and Staphylococcal nuclease domain containing 1 (SND1) are overexpressed and interact in diverse cancer types. The structural mechanism of their interaction remains unclear. Here we determined the high-resolution crystal structure of MTDH-SND1 complex, which reveals an 11-residue M...

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Udgivet i:Cell Rep
Main Authors: Guo, Feng, Wan, Liling, Zheng, Aiping, Stanevich, Vitali, Wei, Yong, Satyshur, Kenneth A., Shen, Minhong, Lee, Woojong, Kang, Yibin, Xing, Yongna
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4309369/
https://ncbi.nlm.nih.gov/pubmed/25242325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.08.033
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