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Structural Insights into the Tumor-Promoting Function of the MTDH-SND1 Complex
Metadherin (MTDH) and Staphylococcal nuclease domain containing 1 (SND1) are overexpressed and interact in diverse cancer types. The structural mechanism of their interaction remains unclear. Here we determined the high-resolution crystal structure of MTDH-SND1 complex, which reveals an 11-residue M...
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Publicado no: | Cell Rep |
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Main Authors: | , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4309369/ https://ncbi.nlm.nih.gov/pubmed/25242325 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.08.033 |
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