Frequent Disruption of Chromodomain Helicase DNA-Binding Protein 8 (CHD8) and Functionally Associated Chromatin Regulators in Prostate Cancer

Abnormal expression and function of chromatin regulators results in the altered chromatin structure seen in cancer. The chromatin regulator CTCF, its cofactor CHD8, and antagonistic paralogue BORIS have wide-ranging effects on gene regulation. Their concurrent expression and regulation was examined...

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Vydáno v:Neoplasia
Hlavní autoři: Damaschke, Nathan A., Yang, Bing, Blute, Michael L., Lin, Chee Paul, Huang, Wei, Jarrard, David F.
Médium: Artigo
Jazyk:Inglês
Vydáno: Neoplasia Press 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4309256/
https://ncbi.nlm.nih.gov/pubmed/25499215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2014.10.003
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