Frequent Disruption of Chromodomain Helicase DNA-Binding Protein 8 (CHD8) and Functionally Associated Chromatin Regulators in Prostate Cancer

Abnormal expression and function of chromatin regulators results in the altered chromatin structure seen in cancer. The chromatin regulator CTCF, its cofactor CHD8, and antagonistic paralogue BORIS have wide-ranging effects on gene regulation. Their concurrent expression and regulation was examined...

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Publicado en:Neoplasia
Main Authors: Damaschke, Nathan A., Yang, Bing, Blute, Michael L., Lin, Chee Paul, Huang, Wei, Jarrard, David F.
Formato: Artigo
Idioma:Inglês
Publicado: Neoplasia Press 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4309256/
https://ncbi.nlm.nih.gov/pubmed/25499215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2014.10.003
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