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Phosphorylation of Shox2 Is Required for Its Function to Control Sinoatrial Node Formation

BACKGROUND: Inactivation of Shox2, a member of the short‐stature homeobox gene family, leads to defective development of multiple organs and embryonic lethality as a result of cardiovascular defects, including bradycardia and severe hypoplastic sinoatrial node (SAN) and sinus valves, in mice. It has...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Liu, Hongbing, Chen, Chao‐Hui, Ye, Wenduo, Espinoza‐Lewis, Ramón A., Hu, Xuefeng, Zhang, Yanding, Chen, YiPing
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4309068/
https://ncbi.nlm.nih.gov/pubmed/24847033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.114.000796
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