Identification of Hic–5 as a Novel Scaffold for the MKK4/p54 JNK Pathway in the Development of Abdominal Aortic Aneurysms

BACKGROUND: Although increased amounts of reactive oxygen species in the pathogenesis of abdominal aortic aneurysm (AAA) are well documented, the precise molecular mechanisms by which reactive oxygen species induce AAAs have not been fully elucidated. This study focused on the role of hydrogen perox...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Lei, Xiao‐Feng, Kim‐Kaneyama, Joo‐ri, Arita‐Okubo, Shigeko, Offermanns, Stefan, Itabe, Hiroyuki, Miyazaki, Takuro, Miyazaki, Akira
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2014
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4309060/
https://ncbi.nlm.nih.gov/pubmed/24811612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.113.000747
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