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Stereochemistry of polymerization by DNA-dependent RNA-polymerase from Escherichia coli: an investigation with a diastereomeric ATP-analogue.

The phosphodiester bond formation by DNA-dependent RNA-polymerase (RNA nucleotidyltransferase, nucleosidetriphosphate:RNA nucleotidyltransferase, EC 2.7.7.6) can in principle result in retention, inversion, or racemization of configuration at the alpha-phosphorus of the nucleoside 5'-triphospha...

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Detalles Bibliográficos
Main Authors: Eckstein, F, Armstrong, V W, Sternbach, H
Formato: Artigo
Idioma:Inglês
Publicado: 1976
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC430902/
https://ncbi.nlm.nih.gov/pubmed/787980
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