Association of BRCA1/2defects with genomic scores predictive of DNA damage repair deficiency among breast cancer subtypes

INTRODUCTION: Homologous recombination (HR) DNA repair is of clinical relevance in breast cancer. Three DNA-based homologous recombination deficiency (HRD) scores (HRD-loss of heterozygosity score (LOH), HRD-telomeric allelic imbalance score (TAI), and HRD-large-scale state transition score (LST)) h...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Breast Cancer Res
Auteurs principaux: Timms, Kirsten M, Abkevich, Victor, Hughes, Elisha, Neff, Chris, Reid, Julia, Morris, Brian, Kalva, Saritha, Potter, Jennifer, Tran, Thanh V, Chen, Jian, Iliev, Diana, Sangale, Zaina, Tikishvili, Eliso, Perry, Michael, Zharkikh, Andrey, Gutin, Alexander, Lanchbury, Jerry S
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2014
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4308910/
https://ncbi.nlm.nih.gov/pubmed/25475740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-014-0475-x
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires