Unbiased Whole-Genome Amplification Directly From Clinical Samples

Preparation of genomic DNA from clinical samples is a bottleneck in genotyping and DNA sequencing analysis and is frequently limited by the amount of specimen available. We use Multiple Displacement Amplification (MDA) to amplify the whole genome 10,000-fold directly from small amounts of whole bloo...

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Detalhes bibliográficos
Main Authors: Hosono, Seiyu, Faruqi, A. Fawad, Dean, Frank B., Du, Yuefen, Sun, Zhenyu, Wu, Xiaohong, Du, Jing, Kingsmore, Stephen F., Egholm, Michael, Lasken, Roger S.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2003
Assuntos:
Methods
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC430878/
https://ncbi.nlm.nih.gov/pubmed/12695328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.816903
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