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In silico identification of microRNAs predicted to regulate the drug metabolizing cytochrome P450 genes

OBJECTIVE: Cytochrome P450 (CYP) enzymes exhibit high interindividual variability that is not completely explained by known environmental and genetic factors. To further understand this variability, we hypothesized that microRNAs (miRNAs) may regulate CYP expression. METHODS: MiRNA identification al...

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Publicat a:Drug Metab Lett
Autors principals: Ramamoorthy, Anuradha, Skaar, Todd C.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4308728/
https://ncbi.nlm.nih.gov/pubmed/21457141
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