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Modeling Intrinsic Heterogeneity and Growth of Cancer Cells

Intratumoral heterogeneity has been found to be a major cause of drug resistance. Cell-to-cell variation increases as a result of cancer-related alterations, which are acquired by stochastic events and further induced by environmental signals. However, most cellular mechanisms include natural fluctu...

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Detalhes bibliográficos
Publicado no:J Theor Biol
Main Authors: Greene, James M., Levy, Doron, Fung, King L., Silva de Souza, Paloma, Gottesman, Michael M., Lavi, Orit
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4308514/
https://ncbi.nlm.nih.gov/pubmed/25457229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2014.11.017
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