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STING mediates protection against colorectal tumorigenesis by governing the magnitude of intestinal inflammation
STING is a cytoplasmic innate immune sensor for cyclic dinucleotides, which also serves a dual role as an adaptor molecule for a number of intracellular DNA receptors. Although STING has important functions in the host defense against pathogens and autoimmune diseases, its physiological role in canc...
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| Publicado no: | J Immunol |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4308418/ https://ncbi.nlm.nih.gov/pubmed/25320273 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402051 |
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