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A Computational Strategy to Select Optimized Protein Targets for Drug Development toward the Control of Cancer Diseases

In this report, we describe a strategy for the optimized selection of protein targets suitable for drug development against neoplastic diseases taking the particular case of breast cancer as an example. We combined human interactome and transcriptome data from malignant and control cell lines becaus...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Carels, Nicolas, Tilli, Tatiana, Tuszynski, Jack A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4308075/
https://ncbi.nlm.nih.gov/pubmed/25625699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115054
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