Validation of a network-based strategy for the optimization of combinatorial target selection in breast cancer therapy: siRNA knockdown of network targets in MDA-MB-231 cells as an in vitro model for inhibition of tumor development

Network-based strategies provided by systems biology are attractive tools for cancer therapy. Modulation of cancer networks by anticancer drugs may alter the response of malignant cells and/or drive network re-organization into the inhibition of cancer progression. Previously, using systems biology...

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Vydáno v:Oncotarget
Hlavní autoři: Tilli, Tatiana M., Carels, Nicolas, Tuszynski, Jack A., Pasdar, Manijeh
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325356/
https://ncbi.nlm.nih.gov/pubmed/27527857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11055
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