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Purification of 3-hydroxy-3-methylglutaryl-coenzyme A reductase from rat liver.

A procedure for the purification of 3-hydroxy-3-methylglutaryl-coenzyme A reductase [mevalonate: NADP+ oxidoreductase (CoA-acylating); EC 1.1.1.34] solubilized from rat liver microsomes is reported. This enzyme has a specific activity of 9,000-10,000 nmol of mevalonate formed per min/mg of protein....

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Kleinsek, D A, Ranganathan, S, Porter, J W
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 1977
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC430786/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/404638/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.4.1431
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