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Pharmacokinetic Interaction between Efavirenz and Dual Protease Inhibitors in Healthy Volunteers
The combination of efavirenz with HIV-1 protease inhibitors (PI) results in complex interactions secondary to mixed induction and inhibition of oxidative metabolism. ACTG A5043 was a prospective, open-label, controlled, two-period, multiple-dose study with 55 healthy volunteers. The objective of the...
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| Publicado no: | Biopharm Drug Dispos |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4307806/ https://ncbi.nlm.nih.gov/pubmed/18041735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdd.597 |
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