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Pharmacokinetic Interaction between Efavirenz and Dual Protease Inhibitors in Healthy Volunteers

The combination of efavirenz with HIV-1 protease inhibitors (PI) results in complex interactions secondary to mixed induction and inhibition of oxidative metabolism. ACTG A5043 was a prospective, open-label, controlled, two-period, multiple-dose study with 55 healthy volunteers. The objective of the...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Biopharm Drug Dispos
Egile Nagusiak: Ma, Qing, Forrest, Alan, Rosenkranz, Susan L., Para, Michael F., Yarasheski, Kevin E., Reichman, Richard C., Morse, Gene D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4307806/
https://ncbi.nlm.nih.gov/pubmed/18041735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdd.597
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