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Relative conformational rigidity in oxytocin and (1-penicillamine)-oxytocin: a proposal for the relationship of conformational flexibility to peptide hormone agonism and antagonism.

A comparative study of the proton and carbon-13 nuclear magnetic resonance spectral parameters of the peptide hormone oxytocin and of its competitive inhibitor [1-L-penicillamine]oxytocin has been made, and the results analyzed in terms of comparative conformational and dynamic properties. The resul...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Meraldi, J P, Hruby, V J, Brewster, A I
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 1977
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC430763/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/266179/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.4.1373
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