Systemic Delivery of Protein Nanocages Bearing CTT Peptides for Enhanced Imaging of MMP-2 Expression in Metastatic Tumor Models

Matrix metalloproteinase 2 (MMP-2) in metastatic cancer tissue, which is associated with a poor prognosis, is a potential target for tumor imaging in vivo. Here, we describe a metastatic cancer cell-targeted protein nanocage. An MMP-2-binding peptide, termed CTT peptide (CTTHWGFTLC), was conjugated...

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Pubblicato in:Int J Mol Sci
Autori principali: Kawano, Takahito, Murata, Masaharu, Piao, Jing Shu, Narahara, Sayoko, Hamano, Nobuhito, Kang, Jeong-Hun, Hashizume, Makoto
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4307240/
https://ncbi.nlm.nih.gov/pubmed/25547485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms16010148
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