Exosomes from adipose tissue-derived mesenchymal stem cells ameliorate histone-induced acute lung injury by activating the PI3K/Akt pathway in endothelial cells

BACKGROUND: Mesenchymal stem cells (MSCs), including adipose-derived mesenchymal stem cells (ADSCs), have been shown to attenuate organ damage in acute respiratory distress syndrome (ARDS) and sepsis; however, the underlying mechanisms are not fully understood. In this study, we aimed to explore the...

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Bibliographic Details
Published in:Stem Cell Res Ther
Main Authors: Mizuta, Yukie, Akahoshi, Tomohiko, Guo, Jie, Zhang, Shuo, Narahara, Sayoko, Kawano, Takahito, Murata, Masaharu, Tokuda, Kentaro, Eto, Masatoshi, Hashizume, Makoto, Yamaura, Ken
Format: Artigo
Language:Inglês
Published: BioMed Central 2020
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7691956/
https://ncbi.nlm.nih.gov/pubmed/33246503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-02015-9
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