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Dual role of Zn2+ as inhibitor and activator of fructose 1,6-bisphosphatase of rat liver.
At neutral pH, Zn2+ is a potent and specific inhibitor of rat liver fructose 1,6-bisphosphatase (EC 3.1.3.11; D-fructose-1,6-bisphosphate 1-phosphohydrolase). Inhibition by Zn2+ is uncompetitive with respect to the activating cations Mg2+ and Mn2+, and the kinetic data suggest that the enzyme posses...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1976
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC430714/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8778/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.73.8.2692 |
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