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Dual role of Zn2+ as inhibitor and activator of fructose 1,6-bisphosphatase of rat liver.

At neutral pH, Zn2+ is a potent and specific inhibitor of rat liver fructose 1,6-bisphosphatase (EC 3.1.3.11; D-fructose-1,6-bisphosphate 1-phosphohydrolase). Inhibition by Zn2+ is uncompetitive with respect to the activating cations Mg2+ and Mn2+, and the kinetic data suggest that the enzyme posses...

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Detalles Bibliográficos
Main Authors: Tejwani, G A, Pedrosa, F O, Pontremoli, S, Horecker, B L
Formato: Artigo
Idioma:Inglês
Publicado: 1976
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC430714/
https://ncbi.nlm.nih.gov/pubmed/8778
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