Araguspongine C Induces Autophagic Death in Breast Cancer Cells through Suppression of c-Met and HER2 Receptor Tyrosine Kinase Signaling

Receptor tyrosine kinases are key regulators of cellular growth and proliferation. Dysregulations of receptor tyrosine kinases in cancer cells may promote tumorigenesis by multiple mechanisms including enhanced cell survival and inhibition of cell death. Araguspongines represent a group of macrocycl...

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Publicado no:Mar Drugs
Main Authors: Akl, Mohamed R., Ayoub, Nehad M., Ebrahim, Hassan Y., Mohyeldin, Mohamed M., Orabi, Khaled Y., Foudah, Ahmed I., El Sayed, Khalid A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4306938/
https://ncbi.nlm.nih.gov/pubmed/25580621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md13010288
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